The berries of American mountain-ash are eaten by numerous species of birds, including ruffed grouse, ptarmigans, sharp-tailed grouse, blue grouse, American robins, other thrushes, waxwings, jays, and small mammals, such as squirrels and rodents.
American mountain-ash is a preferred browse for moose and white-tailed deer. Moose will eat foliage, twigs, and bark. Up to 80 percent of American mountain-ash stems were browsed by moose in control plots adjacent to exclosures on Isle Royale. Fishers, martens, snowshoe hares, and ruffed grouse also browse American mountain-ash